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The use of antimicrobial catheters is supported by randomized trials and economic evaluations establishing their efficacy.(15,16) A 2008 economic analysis from the National Health Trust of the United Kingdom concluded that anti-infective CVCs should be integrated into standard care because they are clinically effective, relatively inexpensive, and offer potential cost savings, but that "the use of these anti-infective catheters without the appropriate use of other practical care initiatives will have only a limited effect on the prevention of CRBSIs."(15) Additional items that reduce the risk of contamination or infection of the catheter include prefilled syringes, disinfecting caps for access points, antimicrobial sponges or dressings for the insertion site, and catheter securement devices